ITGA6 anticorps (FITC)

N° du produit ABIN118232

L’anticorps Rat Monoclonal anti-ITGA6 a été validé pour FACS. Il convient pour détecter ITGA6 dans des échantillons de Humain, Souris, Chien, Porc, Singe et Mouton.

Aperçu rapide pour ITGA6 anticorps (FITC) (ABIN118232)

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivité: Humain, Souris, Chien, Porc, Singe, Mouton

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA6 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: NKI-GoH3

Détail du produit anti-ITGA6 anticorps (FITC)

Specificité: This antibody recognises CD49F (VLA-6 alpha chain). Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin.

Purification: Affinity chromatography on Protein G

Immunogène: BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ITGA6

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Autre désignation: CD49f / ITGA6

Sujet: CD49f is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6

ID gène: 3655

NCBI Accession: NP_000201

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex